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The adenovirus protein Gam1 interferes with sumoylation of histone deacetylase 1
The adenovirus early gene product Gam1 is crucial for virus replication and induces certain cellular genes by inactivating histone deacetylase 1 (HDAC1). We demonstrate that Gam1 (i) destroys promyelocitic leukemia nuclear bodies, (ii) delocalizes SUMO-1 into the cytoplasm and (iii) influences the S...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2002
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1307602/ https://ncbi.nlm.nih.gov/pubmed/12393750 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kvf213 |
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