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Intersubunit bridging by Na(+) ions as a rationale for the unusual stability of the c-rings of Na(+)-translocating F(1)F(0) ATP synthases

The oligomeric c-rings of Na(+)-translocating F(1)F(0) ATP synthases exhibit unusual stability, resisting even boiling in SDS. Here, we show that the molecular basis for this remarkable property is intersubunit crossbridging by Na(+) or Li(+) ions. The heat stability of c(11) was dependent on the pr...

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Bibliographic Details
Main Authors: Meier, Thomas, Dimroth, Peter
Format: Artigo
Language:Inglês
Published: 2002
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1307599/
https://ncbi.nlm.nih.gov/pubmed/12393753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/embo-reports/kvf216
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