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Factor XIII Val34Leu polymorphism and γ-chain cross-linking at the site of microvascular injury in healthy and coumadin-treated subjects
Fibrin cross-linking by activated factor (F)XIII is essential for clot stability. In vitro, a common Leu34 polymorphism of the FXIII A-subunit increases the rate of thrombin-mediated FXIII activation, but not cross-linking activity upon complete FXIII activation. The effect of FXIII Val34Leu polymor...
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| Asıl Yazarlar: | , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2005
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1307169/ https://ncbi.nlm.nih.gov/pubmed/16102108 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1538-7836.2005.01509.x |
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