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Factor XIII Val34Leu polymorphism and γ-chain cross-linking at the site of microvascular injury in healthy and coumadin-treated subjects

Fibrin cross-linking by activated factor (F)XIII is essential for clot stability. In vitro, a common Leu34 polymorphism of the FXIII A-subunit increases the rate of thrombin-mediated FXIII activation, but not cross-linking activity upon complete FXIII activation. The effect of FXIII Val34Leu polymor...

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Detaylı Bibliyografya
Asıl Yazarlar: Undas, Anetta, Brzezinska-Kolarz, Beata, Brummel, Kathleen, Musial, Jacek, Szczeklik, Andrzej, Mann, Kenneth G.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2005
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1307169/
https://ncbi.nlm.nih.gov/pubmed/16102108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1538-7836.2005.01509.x
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