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Molecular Analysis of the Pathogenicity Locus and Polymorphism in the Putative Negative Regulator of Toxin Production (TcdC) among Clostridium difficile Clinical Isolates

The pathogenicity locus (PaLoc) of Clostridium difficile contains toxin A and B genes and three accessory genes, including tcdD and tcdC, which are supposed to code for the positive and negative regulators of toxin expression, respectively. Different studies have described variations in C. difficile...

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Détails bibliographiques
Auteurs principaux: Spigaglia, Patrizia, Mastrantonio, Paola
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2002
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC130716/
https://ncbi.nlm.nih.gov/pubmed/12202595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JCM.40.9.3470-3475.2002
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