Vaccination with the Recombinant Brucella Outer Membrane Protein 31 or a Derived 27-Amino-Acid Synthetic Peptide Elicits a CD4(+) T Helper 1 Response That Protects against Brucella melitensis Infection

The immunogenicity and protective efficacy of the recombinant 31-kDa outer membrane protein from Brucella melitensis (rOmp31), administered with incomplete Freund's adjuvant, were evaluated in mice. Immunization of BALB/c mice with rOmp31 conferred protection against B. ovis and B. melitensis i...

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Main Authors: Cassataro, Juliana, Estein, Silvia M., Pasquevich, Karina A., Velikovsky, Carlos A., de la Barrera, Silvia, Bowden, Raúl, Fossati, Carlos A., Giambartolomei, Guillermo H.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2005
Assuntos:
Microbial Immunity and Vaccines
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1307072/
https://ncbi.nlm.nih.gov/pubmed/16299302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.12.8079-8088.2005
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