Conjugates of Group A and W135 Capsular Polysaccharides of Neisseria meningitidis Bound to Recombinant Staphylococcus aureus Enterotoxin C1: Preparation, Physicochemical Characterization, and Immunological Properties in Mice

Neisseria meningitidis groups A (GAM) and W135 capsular polysaccharides (CPs) were bound to recombinant Staphylococcus aureus enterotoxin C1 (rSEC). The CPs were activated with 1-cyano-4-dimethylaminopyridinium tetrafluoroborate and then bound to adipic acid dihydrazide derivatives of rSEC. Synthese...

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Autors principals: Jin, Zhigang, Bohach, Gregory A., Shiloach, Joseph, Norris, Scott E., Freedberg, Darón I., Deobald, Claudia, Coxon, Bruce, Robbins, John B., Schneerson, Rachel
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
Matèries:
Microbial Immunity and Vaccines
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1307062/
https://ncbi.nlm.nih.gov/pubmed/16299279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.12.7887-7893.2005
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