Reduction of Astrogliosis by Early Treatment of Pneumococcal Meningitis Measured by Simultaneous Imaging, In Vivo, of the Pathogen and Host Response

We developed a method for simultaneous in vivo biophotonic monitoring of pneumococcal meningitis and the accompanying neuronal injury in live transgenic mice. Streptococcus pneumoniae engineered for bioluminescence (lux) was used for direct visualization of disease progression and antibiotic treatme...

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Bibliografiset tiedot
Päätekijät: Kadurugamuwa, Jagath L., Modi, Kshitij, Coquoz, Olivier, Rice, Brad, Smith, Steven, Contag, Pamela R., Purchio, Tony
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2005
Aiheet:
Cellular Microbiology: Pathogen-Host Cell Molecular Interactions
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1307043/
https://ncbi.nlm.nih.gov/pubmed/16299273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.12.7836-7843.2005
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