Toxoplasma gondii-Specific Immunoglobulin M Limits Parasite Dissemination by Preventing Host Cell Invasion

An important role for immunoglobulin M (IgM) during early acute virulent Toxoplasma gondii infection was identified using IgM(−/−) mice that lack surface and secretory IgM but maintain normal B-cell functionality and isotype class switching. Following intraperitoneal inoculation with the virulent RH...

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Autors principals: Couper, Kevin N., Roberts, Craig W., Brombacher, Frank, Alexander, James, Johnson, Lawrence L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2005
Matèries:
Fungal and Parasitic Infections
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1307022/
https://ncbi.nlm.nih.gov/pubmed/16299300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.12.8060-8068.2005
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