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Metapopulation dynamics and spatial heterogeneity in cancer

With the advent of drugs targeting specific molecular defects in cancerous cells [Gorre, M. E., et al. (2001) Science 293, 876–880], it is important to understand the degree of genetic heterogeneity present in tumor cell populations and the rules that govern microdiversity in human cancer. Here, we...

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Bibliografische gegevens
Hoofdauteurs: González-García, Isabel, Solé, Ricard V., Costa, José
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The National Academy of Sciences 2002
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC130590/
https://ncbi.nlm.nih.gov/pubmed/12351679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.202139299
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