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C-reactive protein binds to both oxidized LDL and apoptotic cells through recognition of a common ligand: Phosphorylcholine of oxidized phospholipids

C-reactive protein (CRP) is an acute-phase protein that binds specifically to phosphorylcholine (PC) as a component of microbial capsular polysaccharide and participates in the innate immune response against microorganisms. CRP elevation also is a major risk factor for cardiovascular disease. We pre...

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Detalhes bibliográficos
Main Authors: Chang, Mi-Kyung, Binder, Christoph J., Torzewski, Michael, Witztum, Joseph L.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC130583/
https://ncbi.nlm.nih.gov/pubmed/12244213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.192399699
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