A Stopped-Flow Kinetic Study of the Assembly of Nonviral Gene Delivery Complexes

Stopped-flow circular dichroism and fluorescence spectroscopy are used to characterize the assembly of complexes consisting of plasmid DNA bound to the cationic lipids dimethyldioctadecylammonium bromide and 1, 2-dioleoyl- 3-trimethylammonium-propane and a series of polyamidoamine dendrimers. The ki...

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Autores principales: Braun, Chad S., Fisher, Mark T., Tomalia, Donald A., Koe, Gary S., Koe, Janet G., Middaugh, C. Russell
Formato: Artigo
Lenguaje:Inglês
Publicado: Biophysical Society 2005
Materias:
Nucleic Acids
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1305645/
https://ncbi.nlm.nih.gov/pubmed/15805171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.055202
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