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Differential Labeling of Myosin V Heads with Quantum Dots Allows Direct Visualization of Hand-Over-Hand Processivity

The double-headed myosin V molecular motor carries intracellular cargo processively along actin tracks in a hand-over-hand manner. To test this hypothesis at the molecular level, we observed single myosin V molecules that were differentially labeled with quantum dots having different emission spectr...

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Autores principales: Warshaw, David M., Kennedy, Guy G., Work, Steven S., Krementsova, Elena B., Beck, Samantha, Trybus, Kathleen M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Biophysical Society 2005
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1305523/
https://ncbi.nlm.nih.gov/pubmed/15764654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.061903
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