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Mechanism of Membrane Activity of the Antibiotic Trichogin GA IV: A Two-State Transition Controlled by Peptide Concentration

Synthetic fluorescent analogs of the natural lipopeptide trichogin GA IV were used to investigate the peptide position and orientation in model membranes. A translocation assay based on Förster energy transfer indicates that trichogin is associated to both the outer and inner leaflet of the membrane...

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Detalhes bibliográficos
Main Authors: Mazzuca, Claudia, Stella, Lorenzo, Venanzi, Mariano, Formaggio, Fernando, Toniolo, Claudio, Pispisa, Basilio
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2005
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1305488/
https://ncbi.nlm.nih.gov/pubmed/15722429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.056077
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