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A Vibrational Spectral Maker for Probing the Hydrogen-Bonding Status of Protonated Asp and Glu Residues

Hydrogen bonding is a fundamental element in protein structure and function. Breaking a single hydrogen bond may impair the stability of a protein. We report an infrared vibrational spectral marker for probing the hydrogen-bond number for buried, protonated Asp or Glu residues in proteins. Ab initio...

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Bibliografiske detaljer
Main Authors: Nie, Beining, Stutzman, Jerrod, Xie, Aihua
Format: Artigo
Sprog:Inglês
Udgivet: Biophysical Society 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1305378/
https://ncbi.nlm.nih.gov/pubmed/15653739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.047639
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