Surface Behavior and Lipid Interaction of Alzheimer β-Amyloid Peptide 1–42: A Membrane-Disrupting Peptide

Amyloid aggregates, found in patients that suffer from Alzheimer's disease, are composed of fibril-forming peptides in a β-sheet conformation. One of the most abundant components in amyloid aggregates is the β-amyloid peptide 1–42 (Aβ 1–42). Membrane alterations may proceed to cell death by eit...

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Hlavní autoři: Ambroggio, Ernesto E., Kim, Dennis H., Separovic, Frances, Barrow, Colin J., Barnham, Kevin J., Bagatolli, Luis A., Fidelio, Gerardo D.
Médium: Artigo
Jazyk:Inglês
Vydáno: Biophysical Society 2005
Témata:
Membranes
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1305366/
https://ncbi.nlm.nih.gov/pubmed/15681641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.055582
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