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Optimizing Transport of Metabolites through Large Channels: Molecular Sieves with and without Binding

Using a diffusion model of molecules moving through a pore, we rationalize why biological channels have an affinity for the molecules they have evolved to translocate.

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Detalhes bibliográficos
Main Authors: Berezhkovskii, Alexander M., Bezrukov, Sergey M.
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1305284/
https://ncbi.nlm.nih.gov/pubmed/15626697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.057588
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