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Repetitive Transient Depolarizations of the Inner Mitochondrial Membrane Induced by Proton Pumping

Single mitochondria show the spontaneous fluctuations of ΔΨm. In this study, to examine the mechanism of the fluctuations, we observed ΔΨm in single isolated heart mitochondria using time-resolved fluorescence microscopy. Addition of malate, succinate, or ascorbate plus TMPD to mitochondria induced...

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Detalhes bibliográficos
Main Authors: Hattori, Tomohiro, Watanabe, Koichi, Uechi, Yukiko, Yoshioka, Hisashi, Ohta, Yoshihiro
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1305282/
https://ncbi.nlm.nih.gov/pubmed/15653749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.041483
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