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Protein nitration is mediated by heme and free metals through Fenton-type chemistry: An alternative to the NO/O [Formula: see text] reaction

The chemical origins of nitrated tyrosine residues (NT) formed in proteins during a variety of pathophysiological conditions remain controversial. Although numerous studies have concluded that NT is a signature for peroxynitrite (ONOO(−)) formation, other works suggest the primary involvement of per...

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Hlavní autoři: Thomas, Douglas D., Espey, Michael Graham, Vitek, Michael P., Miranda, Katrina M., Wink, David A.
Médium: Artigo
Jazyk:Inglês
Vydáno: The National Academy of Sciences 2002
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC130522/
https://ncbi.nlm.nih.gov/pubmed/12226478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.202312699
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