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Knowledge-Based Elastic Potentials for Docking Drugs or Proteins with Nucleic Acids

Elastic ellipsoidal functions defined by the observed hydration patterns around the DNA bases provide a new basis for measuring the recognition of ligands in the grooves of double-helical structures. Here a set of knowledge-based potentials suitable for quantitative description of such behavior is e...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Ge, Wei, Schneider, Bohdan, Olson, Wilma K.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Biophysical Society 2005
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC1305121/
https://ncbi.nlm.nih.gov/pubmed/15501936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.043612
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