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Modeling the Effect of Deregulated Proliferation and Apoptosis on the Growth Dynamics of Epithelial Cell Populations In Vitro

We present a three-dimensional individual cell-based, biophysical model to study the effect of normal and malfunctioning growth regulation and control on the spatial-temporal organization of growing cell populations in vitro. The model includes explicit representations of typical epithelial cell gro...

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Detalhes bibliográficos
Main Authors: Galle, Jörg, Loeffler, Markus, Drasdo, Dirk
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1305039/
https://ncbi.nlm.nih.gov/pubmed/15475585
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.041459
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