Molecular Mechanisms and Kinetics between DNA and DNA Binding Ligands

Mechanical properties of single double-stranded DNA (dsDNA) in the presence of different binding ligands were analyzed in optical-tweezers experiments with subpiconewton force resolution. The binding of ligands to DNA changes the overall mechanic response of the dsDNA molecule. This fundamental prop...

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Bibliografiske detaljer
Main Authors: Sischka, Andy, Toensing, Katja, Eckel, Rainer, Wilking, Sven David, Sewald, Norbert, Ros, Robert, Anselmetti, Dario
Format: Artigo
Sprog:Inglês
Udgivet: The Biophysical Society 2005
Fag:
Nucleic Acids
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1305017/
https://ncbi.nlm.nih.gov/pubmed/15516529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.103.036293
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