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Characterization of Interaction between Cationic Lipid-Oligonucleotide Complexes and Cellular Membrane Lipids Using Confocal Imaging and Fluorescence Correlation Spectroscopy

Complexes formed by cationic liposomes and single-strand oligodeoxynucleotides (CL-ODN) are promising delivery systems for antisense therapy. ODN release from the complexes is an essential step for inhibiting activity of antisense drugs. We applied fluorescence correlation spectroscopy and confocal...

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Detalhes bibliográficos
Main Authors: Gordon, Sean Patrick, Berezhna, Svitlana, Scherfeld, Dag, Kahya, Nicoletta, Schwille, Petra
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1305008/
https://ncbi.nlm.nih.gov/pubmed/15516528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.043133
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