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Effects of Phenylalanine Substitutions in Gramicidin A on the Kinetics of Channel Formation in Vesicles and Channel Structure in SDS Micelles

The common occurrence of Trp residues at the aqueous-lipid interface region of transmembrane channels is thought to be indicative of its importance for insertion and stabilization of the channel in membranes. To further investigate the effects of Trp→Phe substitution on the structure and function of...

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Detalles Bibliográficos
Main Authors: Jordan, J. B., Easton, P. L., Hinton, J. F.
Formato: Artigo
Idioma:Inglês
Publicado: The Biophysical Society 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1305000/
https://ncbi.nlm.nih.gov/pubmed/15501932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.047456
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