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Kinetics of Protein-DNA Interaction: Facilitated Target Location in Sequence-Dependent Potential

Recognition and binding of specific sites on DNA by proteins is central for many cellular functions such as transcription, replication, and recombination. In the process of recognition, a protein rapidly searches for its specific site on a long DNA molecule and then strongly binds this site. Here we...

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Detalhes bibliográficos
Main Authors: Slutsky, Michael, Mirny, Leonid A.
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304911/
https://ncbi.nlm.nih.gov/pubmed/15465864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.050765
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