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Functional Characterization of a Small Conductance GIRK Channel in Rat Atrial Cells

Muscarinic K(+) (K(ACh)) channels are key determinants of the inhibitory synaptic transmission in the heart. These channels are heterotetramers consisting of two homologous subunits, G-protein-gated inwardly rectifying K(+) (GIRK)1 and GIRK4, and have unitary conductance of ∼35 pS with symmetrical 1...

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Hlavní autoři: Nikolov, Emil N., Ivanova-Nikolova, Tatyana T.
Médium: Artigo
Jazyk:Inglês
Vydáno: Biophysical Society 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304783/
https://ncbi.nlm.nih.gov/pubmed/15507689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.103.039487
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