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Formation of Partially Ordered Oligomers of Amyloidogenic Hexapeptide (NFGAIL) in Aqueous Solution Observed in Molecular Dynamics Simulations

A combined total of more than 600.0 ns molecular dynamics simulations with explicit solvent have been carried on systems containing either four peptides or a single peptide to investigate the early-stage aggregation process of an amyloidogenic hexapeptide, NFGAIL (residues 22–27 of the human islet a...

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Detalhes bibliográficos
Main Authors: Wu, Chun, Lei, Hongxing, Duan, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304773/
https://ncbi.nlm.nih.gov/pubmed/15326028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.047076
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