Sizing DNA Using a Nanometer-Diameter Pore

Each species from bacteria to human has a distinct genetic fingerprint. Therefore, a mechanism that detects a single molecule of DNA represents the ultimate analytical tool. As a first step in the development of such a tool, we have explored using a nanometer-diameter pore, sputtered in a nanometer-...

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Main Authors: Heng, Jiunn B., Ho, Chuen, Kim, Taekyung, Timp, Rolf, Aksimentiev, Aleksij, Grinkova, Yelena V., Sligar, Stephen, Schulten, Klaus, Timp, Gregory
Format: Artigo
Sprog:Inglês
Udgivet: Biophysical Society 2004
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304707/
https://ncbi.nlm.nih.gov/pubmed/15326034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.041814
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