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The Force Exerted by a Muscle Cross-Bridge Depends Directly on the Strength of the Actomyosin Bond

Myosin produces force in a cyclic interaction, which involves alternate tight binding to actin and to ATP. We have investigated the energetics associated with force production by measuring the force generated by skinned muscle fibers as the strength of the actomyosin bond is changed. We varied the s...

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Bibliographic Details
Main Authors: Karatzaferi, Christina, Chinn, Marc K., Cooke, Roger
Format: Artigo
Language:Inglês
Published: Biophysical Society 2004
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304672/
https://ncbi.nlm.nih.gov/pubmed/15454448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.039909
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