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Effects of the Geometry of the Immunological Synapse on the Delivery of Effector Molecules

Recent experiments focusing on the function of the immunological synapse formed between a T cell and an antigen-presenting cell raise many questions about its purpose. We examine the proposal that the close apposition of the cell membranes in the central region of the synapse acts to focus T-cell se...

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Detalhes bibliográficos
Main Authors: Coombs, Daniel, Goldstein, Byron
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304647/
https://ncbi.nlm.nih.gov/pubmed/15454424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.045674
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