Ca(2+) and Ionic Strength Dependencies of S1-ADP Binding to Actin-Tropomyosin-Troponin: Regulatory Implications

Skeletal and cardiac muscle contraction are inhibited by the actin-associated complex of tropomyosin-troponin. Binding of Ca(2+) to troponin or binding of ATP-free myosin to actin reverses this inhibition. Ca(2+) and ATP-free myosin stabilize different tropomyosin-actin structural arrangements. The...

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Bibliographic Details
Main Authors:	Gafurov, Boris, Chen, Yi-Der, Chalovich, Joseph M.
Format:	Artigo
Language:	Inglês
Published:	Biophysical Society 2004
Subjects:	Muscle and Contractility
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC1304587/ https://ncbi.nlm.nih.gov/pubmed/15345561 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.043364
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Ca(2+) and Ionic Strength Dependencies of S1-ADP Binding to Actin-Tropomyosin-Troponin: Regulatory Implications

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