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On the Theory of Noncovalent Binding

It is widely accepted that the binding constant of a receptor and ligand can be written as a two-body integral involving the interaction energy of the receptor and the ligand. Interestingly, however, three different theories of binding in the literature dictate three distinct integrals. The present...

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Main Authors: Mihailescu, Mihail, Gilson, Michael K.
Formato: Artigo
Idioma:Inglês
Publicado: Biophysical Society 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304346/
https://ncbi.nlm.nih.gov/pubmed/15240441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.103.031682
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