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Model of Creation and Evolution of Stable Electropores for DNA Delivery

Electroporation, in which electric pulses create transient pores in the cell membrane, is becoming an important technique for gene therapy. To enable entry of supercoiled DNA into cells, the pores should have sufficiently large radii (>10 nm), remain open long enough for the DNA chain to enter th...

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Detalhes bibliográficos
Main Authors: Smith, Kyle C., Neu, John C., Krassowska, Wanda
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304151/
https://ncbi.nlm.nih.gov/pubmed/15111399
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