The N-Terminal Domain of RTX Toxin ApxI of Actinobacillus pleuropneumoniae Elicits Protective Immunity in Mice

We expressed three Actinobacillus pleuropneumoniae ApxI deletion derivatives to map the domain that could induce protective immunity. Antiserum to ApxI N-terminal covered by residues 40 to 380 was found to neutralize ApxI hemolytic activity but not ApxIII cytotoxicity. When used as a subunit vaccine...

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Publicado en:	Infect Immun
Autores principales:	Seah, J. N., Frey, J., Kwang, J.
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 2002
Materias:	Molecular Pathogenesis
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC130407/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12379729/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.70.11.6464-6467.2002
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