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Metastable Network Model of Protein Transport through Nuclear Pores

To reconcile the observed selectivity and the high rate of translocation of cargo-importin complexes through nuclear pores, we propose that the core of the nuclear pore complex is blocked by a metastable network of phenylalanine and glycine nucleoporins. Although the network arrests the unfacilitate...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kustanovich, T., Rabin, Y.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Biophysical Society 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1304054/
https://ncbi.nlm.nih.gov/pubmed/15041643
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