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Force Spectroscopy with a Small Dithering of AFM Tip: A Method of Direct and Continuous Measurement of the Spring Constant of Single Molecules and Molecular Complexes

A new method of direct and continuous measurement of the spring constant of single molecule or molecular complex is elaborated. To that end the standard force spectroscopy technique with functionalized tips and samples is combined with a small dithering of the tip. The change of the dithering amplit...

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Detalhes bibliográficos
Main Authors: Chtcheglova, Lilia A., Shubeita, George T., Sekatskii, Sergey K., Dietler, Giovanni
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1303910/
https://ncbi.nlm.nih.gov/pubmed/14747352
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