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Sterol Structure and Sphingomyelin Acyl Chain Length Modulate Lateral Packing Elasticity and Detergent Solubility in Model Membranes

Membrane microdomains, such as caveolae and rafts, are enriched in cholesterol and sphingomyelin, display liquid-ordered phase properties, and putatively function as protein organizing platforms. The goal of this investigation was to identify sterol and sphingomyelin structural features that modulat...

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Autori principali: Li, Xin-Min, Momsen, Maureen M., Brockman, Howard L., Brown, Rhoderick E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Biophysical Society 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1303681/
https://ncbi.nlm.nih.gov/pubmed/14645069
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