Evidence Inconsistent with a Negative Influence of T Helper 2 Cells on Protection Afforded by a Dominant T Helper 1 Response against Mycobacterium tuberculosis Lung Infection in Mice

Mice incapable of generating an efficient Th2 response because of functional deletion of the genes for signal transducer and activation of transcription 6 (Stat6), interleukin-4 receptor alpha chain (IL-4Rα), or IL-4 plus IL-13 (IL-4/IL-13) were no more resistant than wild-type (WT) mice to airborne...

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Pubblicato in:	Infect Immun
Autori principali:	Jung, Yu-Jin, LaCourse, Ronald, Ryan, Lynn, North, Robert J.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 2002
Soggetti:	Host Response and Inflammation
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC130368/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12379724/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/IAI.70.11.6436-6443.2002
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