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What Really Prevents Proton Transport through Aquaporin? Charge Self-Energy versus Proton Wire Proposals

The nature of the control of water/proton selectivity in biological channels is a problem of a fundamental importance. Most studies of this issue have proposed that an interference with the orientational requirements of the so-called proton wire is the source of selectivity. The elucidation of the s...

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Detalhes bibliográficos
Main Authors: Burykin, Anton, Warshel, Arieh
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1303673/
https://ncbi.nlm.nih.gov/pubmed/14645061
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