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Distinct Quantal Features of AMPA and NMDA Synaptic Currents in Hippocampal Neurons: Implication of Glutamate Spillover and Receptor Saturation

Excitatory postsynaptic currents (EPSCs) were studied in the CA1 pyramidal cells of rat hippocampal slices. Components mediated by α-amino-3-hydroxy-5-methylisoxazole-4-proprionic acid (AMPA) and by N-methyl-D-aspartate (NMDA) receptors were separated pharmacologically. Quantal parameters of AMPA an...

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Detalhes bibliográficos
Main Authors: Pankratov, Yuri V., Krishtal, Oleg A.
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1303615/
https://ncbi.nlm.nih.gov/pubmed/14581239
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