Detergents Destabilize the Cubic Phase of Monoolein: Implications for Membrane Protein Crystallization

The in meso method for membrane protein crystallization uses a lipidic cubic phase as the hosting medium. The cubic phase provides a lipid bilayer into which the protein presumably reconstitutes and from which protein crystals nucleate and grow. The solutions used to spontaneously form the protein-e...

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Bibliographic Details
Main Authors: Misquitta, Y., Caffrey, M.
Format: Artigo
Language:Inglês
Published: Biophysical Society 2003
Subjects:
Membranes
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1303585/
https://ncbi.nlm.nih.gov/pubmed/14581209
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