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Ionic Currents in the Human Serotonin Transporter Reveal Inconsistencies in the Alternating Access Hypothesis

We have investigated the conduction states of human serotonin transporter (hSERT) using the voltage clamp, cut-open frog oocyte method under different internal and external ionic conditions. Our data indicate discrepancies in the alternating access model of cotransport, which cannot consistently exp...

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Detalhes bibliográficos
Main Authors: Adams, Scott V., DeFelice, Louis J.
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1303331/
https://ncbi.nlm.nih.gov/pubmed/12944272
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