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Thermodynamics of α- and β-Structure Formation in Proteins

An atomic protein model with a minimalistic potential is developed and then tested on an α-helix and a β-hairpin, using exactly the same parameters for both peptides. We find that melting curves for these sequences to a good approximation can be described by a simple two-state model, with parameters...

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Autori principali: Irbäck, Anders, Samuelsson, Björn, Sjunnesson, Fredrik, Wallin, Stefan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Biophysical Society 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1303323/
https://ncbi.nlm.nih.gov/pubmed/12944264
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