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The Shape Parameter of Liposomes and DNA-Lipid Complexes Determined by Viscometry Utilizing Small Sample Volumes

A minicapillary viscometer utilizing <0.5 ml of sample at a volume fraction of <0.1% is described. The calculated a/b of DPPC/DPPG multilamellar liposome was 1.14 as prolate ellipsoids and a/b of dioleoylpropyltrimethyl ammonium methylsulfate-DNA complex at a charge ratio of 4:1 (+/−) was 3.7...

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Detalhes bibliográficos
Main Authors: Sun, Y., Li, X., Düzgüneş, N., Takaoka, Y., Ohi, S., Hirota, S.
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1303240/
https://ncbi.nlm.nih.gov/pubmed/12885666
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