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Regulatory Proteins Alter Nucleotide Binding to Acto-Myosin of Sliding Filaments in Motility Assays

The sliding speed of unregulated thin filaments in motility assays is only about half that of the unloaded shortening velocity of muscle fibers. The addition of regulatory proteins, troponin and tropomyosin, is known to increase the sliding speed of thin filaments in the in vitro motility assay. To...

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Bibliographic Details
Main Authors: Homsher, E., Nili, M., Chen, I. Y., Tobacman, L. S.
Format: Artigo
Language:Inglês
Published: Biophysical Society 2003
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1303225/
https://ncbi.nlm.nih.gov/pubmed/12885651
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