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Calmodulin Modulates Initiation but Not Termination of Spontaneous Ca(2+) Sparks in Frog Skeletal Muscle

Calmodulin is a ubiquitous Ca(2+) sensing protein that binds to and modulates the sarcoplasmic reticulum Ca(2+) release channel, ryanodine receptor (RYR). Here we assessed the effects of calmodulin on the local Ca(2+) release properties of RYR in permeabilized frog skeletal muscle fibers. Fluorescen...

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Bibliografiske detaljer
Main Authors: Rodney, George G., Schneider, Martin F.
Format: Artigo
Sprog:Inglês
Udgivet: Biophysical Society 2003
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1303213/
https://ncbi.nlm.nih.gov/pubmed/12885639
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