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An Integrated Model of Epidermal Growth Factor Receptor Trafficking and Signal Transduction

Endocytic trafficking of many types of receptors can have profound effects on subsequent signaling events. Quantitative models of these processes, however, have usually considered trafficking and signaling independently. Here, we present an integrated model of both the trafficking and signaling path...

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Autori principali: Resat, Haluk, Ewald, Jonathan A., Dixon, David A., Wiley, H. Steven
Natura: Artigo
Lingua:Inglês
Pubblicazione: Biophysical Society 2003
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1303198/
https://ncbi.nlm.nih.gov/pubmed/12885624
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