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The Role of the Dielectric Barrier in Narrow Biological Channels: A Novel Composite Approach to Modeling Single-Channel Currents

A composite continuum theory for calculating ion current through a protein channel of known structure is proposed, which incorporates information about the channel dynamics. The approach is utilized to predict current through the Gramicidin A ion channel, a narrow pore in which the applicability of...

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Detalhes bibliográficos
Main Authors: Mamonov, Artem B., Coalson, Rob D., Nitzan, Abraham, Kurnikova, Maria G.
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1302949/
https://ncbi.nlm.nih.gov/pubmed/12770873
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