Distinctive Modulatory Effects of Five Human Auxiliary β(2) Subunit Splice Variants on L-Type Calcium Channel Gating

Sequence analysis of the human genome permitted cloning of five Ca(2+)-channel β(2) splice variants (β(2a)–β(2e)) that differed only in their proximal amino-termini. The functional consequences of such β(2)-subunit diversity were explored in recombinant L-type channels reconstituted in HEK 293 cells...

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Main Authors: Takahashi, Shoji X., Mittman, Scott, Colecraft, Henry M.
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2003
Assuntos:
Channels, Receptors, and Transporters
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1302863/
https://ncbi.nlm.nih.gov/pubmed/12719232
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