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Mechanical Defects of Muscle Fibers with Myosin Light Chain Mutants that Cause Cardiomyopathy
Familial hypertrophic cardiomyopathy is a disease caused by single mutations in several sarcomeric proteins, including the human myosin ventricular regulatory light chain (vRLC). The effects of four of these mutations (A13T, F18L, E22K, and P95A) in vRLC on force generation were determined as a func...
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| Autor principal: | |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Biophysical Society
2003
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1302809/ https://ncbi.nlm.nih.gov/pubmed/12668451 |
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