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Ionic Mechanisms Underlying Spontaneous CA1 Neuronal Firing in Ca(2+)-Free Solution

Hippocampal CA1 neurons exposed to zero-[Ca(2+)] solutions can generate periodic spontaneous synchronized activity in the absence of synaptic function. Experiments using hippocampal slices showed that, after exposure to zero-[Ca(2+)](0) solution, CA1 pyramidal cells depolarized 5–10 mV and started f...

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Bibliographic Details
Main Authors: Shuai, Jianwei, Bikson, Marom, Hahn, Philip J., Lian, Jun, Durand, Dominique M.
Format: Artigo
Language:Inglês
Published: Biophysical Society 2003
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1302778/
https://ncbi.nlm.nih.gov/pubmed/12609911
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